Significance of Platelet Antibodies in Neonatal Thrombocytopenic Purpura Affecting a Pair of Siblings.
نویسندگان
چکیده
A pair of siblings, both of whom had neonatal thrombocytopenic purpura, are described. During the first pregnancy, the mother was given chlorothiazide and the implications of this therapy are considered. At the end of the second pregnancy a platelet iso-antibody was detected in the maternal serum. The possible reason for not detecting this antibody in the serum of the second child is considered.
منابع مشابه
Isoimmune neonatal thrombocytopenic purpura.
Ten cases of isoimmune neonatal thrombocytopenic purpura (4 pairs of siblings and 2 singletons) are described. The condition was diagnosed by excluding other causes of thrombocytopenia , and in 8 cases it was confirmed by detecting antiplatelet antibodies in the mother. Perhaps steroids should be given to affected infants as soon as the condition is diagnosed in order to stabilise the capillary...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 18 شماره
صفحات -
تاریخ انتشار 1965